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KMID : 0900220140210010008
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대한비과학회지
2014 Volume.21 No. 1 p.8 ~ p.14
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Otorhinolaryngologic Application of Stem Cells
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Yoon Byung-Ki
Kim Dong-Kyu
Kim Dae-Woo
Jin Hong-Ryul
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Abstract
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Stem cells can be isolated from almost any tissue in the body and are capable of proliferating in an undifferentiated manner and, under appropriate inductive conditions, differentiating into multiple cell lineages. Numerous studies are being conducted around the world using stem cells in various medical elds, including otorhinolaryn gology. This review provides a brief overview of the method used for human stem cell isolation, the current status of clinical applications in the eld of otorhinolaryngology as well as in general medicine, and lastly, suggests the future potential of stem cells in otorhinolaryngologic surgery. Within the eld of otorhinolaryngology, stem cells have been clinically used or studied in four main areas: bony framework reconstruction, soft tissue augmentation, cartilage repair and wound healing. Outcomes of stem cell application appear promising; however, further basic research and clinical studies with longer follow-up periods are needed to develop safe and successful clinical applications.
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KEYWORD
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Stem Cell, Otorhinolaryngology - Tissue Engineering
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